Electricity Comes to Cocoa Bottom

ocoa Electricity comes to Cocoa Bottom – Essay There are several literary techniques that are used in this poem such as â€Å"lamps†¦Oil† this is very ironic because they have brought old technology to come and see the new technology being unveiled. Also the fact that they are â€Å"waiting for sunset† is ironic because they are replacing natural light with artificial light.Near the beginning there is a Simile used â€Å"Cable was drawn like a pencil line across the sun† This uses one of the main themes of the poem – technology verses nature, it seems that the â€Å"Cable† is taking over from the sun and is sapping some of its power also a â€Å"pencil line† is not as colourful as the sun with the many different shades this implies that the world is going grey and will have less life in it after the technology has â€Å"taken over†.There is also personification and anticipation used in â€Å"A breeze coming home from the s ea held its Breath†; this shows that even nature is aware of how special this event is. Also the â€Å"Bamboo lining the dirt road stopped swaying† even though this is logical being that the wind has stopped it also heightens the sense of anticipation of the grand event. Sibilance is used in â€Å"as soft as chiffon curtains: Closing. Closing. This uses the repeated â€Å"s† sound to give a gentle ending to the verse and the full stop in between the â€Å"Closing† suggests an amount of time has passed. Irony is used again in â€Å"Is there one among us to record this moment? But there was none† this is ironic because the poem is in fact a written record of the moment. The poem is a narrative and you get this feeling of a story all the way through, It has three stanza two long ones and a shorter one the first one is 17 lines and they get smaller to 15 lines then only 6. – couldn’t find much about the form and structure.

Mans Impact N the Environment

Chante Hamilton Maturity Maturity. What makes an individual mature? Maturity comes with age and time. It is the ability to make wise decisions. It is also the way in which people act toward different situations. Maturity can be shown in the way organisms develop. Society claims that females mature faster than males, physically and emotionally. However this is not necessarily true because everyone grows differently. Although maturity has much to do with aging, it can also be seen in the way animals and plants grow. Almost anyone can identify the difference between a mango seedling and a fully developed mangola .The contrast is obvious. A mango seedling is small, hard, bitter and green. On the other hand, a mangola is large in size, bright yellow and succulent due to its maturity. This instantly brings to mind the origin of the word mature. The word is derived from the Latin term ‘maturare’ which means â€Å"to ripen†. We can also see maturity in animals. For exampl e, a toad and a tadpole are completely different in structure. However, a tadpole changes into a toad due to metamorphosis. A tadpole is limited to only a tale and a head and is incredibly. Whereas a toad particularly bulky and has webbed feed, protruding eyes and lacks a tale.Maturity is also shown in the way human beings grow as they age. In this case, some people mature faster than others. The body of an adolescent female is far less developed than an adult female. A mature female has broad hips and large busts compared to younger females who lack such assets. Body maturity also applies to males. When a male is young his entire body has a â€Å"young† look. His shoulders are not broad, his arms look a bit wimpy and he has little to no facial hair. However, a grown male has facial hair, he is taller, his arms and his chest and shoulders are built. Recently I’ve witnessed just how immature some people can get.Politicians of the PLP and FNM exposed each other’s personal life to the nation as if it were concerned anyone. They did this just to gain more votes. Anyone that can stoop this low has to be immature. To be immature is to be mentally primitive. It causes human beings to display a â€Å"childish† attitude towards others. They should have played fair and worked in their constituencies to the best of their abilities. That would have been the mature thing to do. Immaturity is also seen at its best in young children. For example, as a child I would throw the biggest of tantrums whenever I candy and â€Å"no† was the answer.I would cry, scream and throw things over until I accepted the fact that I just was not getting the candy. Now, as an adult I can hear the word â€Å"no† and move on because of the level of maturity I’ve gained over the past few years. The best way to show maturity is to show our knowledge instead of bringing childish acts to the table. Each and every one of us has the ability to do so if we would just think before we act. We should also show respect for our peers and give help where it is due. Maturity is also shown through manners, courteousness and being graceful. All of these things are what makes an individual mature. Mans Impact N the Environment Chante Hamilton Maturity Maturity. What makes an individual mature? Maturity comes with age and time. It is the ability to make wise decisions. It is also the way in which people act toward different situations. Maturity can be shown in the way organisms develop. Society claims that females mature faster than males, physically and emotionally. However this is not necessarily true because everyone grows differently. Although maturity has much to do with aging, it can also be seen in the way animals and plants grow. Almost anyone can identify the difference between a mango seedling and a fully developed mangola .The contrast is obvious. A mango seedling is small, hard, bitter and green. On the other hand, a mangola is large in size, bright yellow and succulent due to its maturity. This instantly brings to mind the origin of the word mature. The word is derived from the Latin term ‘maturare’ which means â€Å"to ripen†. We can also see maturity in animals. For exampl e, a toad and a tadpole are completely different in structure. However, a tadpole changes into a toad due to metamorphosis. A tadpole is limited to only a tale and a head and is incredibly. Whereas a toad particularly bulky and has webbed feed, protruding eyes and lacks a tale.Maturity is also shown in the way human beings grow as they age. In this case, some people mature faster than others. The body of an adolescent female is far less developed than an adult female. A mature female has broad hips and large busts compared to younger females who lack such assets. Body maturity also applies to males. When a male is young his entire body has a â€Å"young† look. His shoulders are not broad, his arms look a bit wimpy and he has little to no facial hair. However, a grown male has facial hair, he is taller, his arms and his chest and shoulders are built. Recently I’ve witnessed just how immature some people can get.Politicians of the PLP and FNM exposed each other’s personal life to the nation as if it were concerned anyone. They did this just to gain more votes. Anyone that can stoop this low has to be immature. To be immature is to be mentally primitive. It causes human beings to display a â€Å"childish† attitude towards others. They should have played fair and worked in their constituencies to the best of their abilities. That would have been the mature thing to do. Immaturity is also seen at its best in young children. For example, as a child I would throw the biggest of tantrums whenever I candy and â€Å"no† was the answer.I would cry, scream and throw things over until I accepted the fact that I just was not getting the candy. Now, as an adult I can hear the word â€Å"no† and move on because of the level of maturity I’ve gained over the past few years. The best way to show maturity is to show our knowledge instead of bringing childish acts to the table. Each and every one of us has the ability to do so if we would just think before we act. We should also show respect for our peers and give help where it is due. Maturity is also shown through manners, courteousness and being graceful. All of these things are what makes an individual mature.

Political Corruption Essay

Wrongdoing on the part of an authority or powerful party through means that are illegitimate, immoral, or incompatible with ethical standards. Corruption often results from patronage and is associated with bribery. In economy, corruption is payment for services or material which the recipient is not due, under law. This may be called bribery. Way back in 200 B.C., Kautilya meticulously described 40 different kinds of corruption in his Arthashastra. He has aptly commented: â€Å"Just as it is impossible not to taste honey or poison when it is at the tip of the tongue, so it is impossible for a government servant not to eat up a bit of revenue. And just as it cannot be found out whether a fish swimming through water drinks or not so also government servants cannot be found out while taking money for themselves.† Corruption is defined as moral depravity and influencing through bribery. Essentially, corruption is the abuse of trust in the interest of private gain. This normally involves business man and government. The extortive type is the kind where the donor is compelled to bribe in order to avoid harm being inflicted upon his person or his interest. It is not difficult to locate the causes of corruption. Corruption breeds at the top and then gradually filters down to the lower levels. Gone are the days when people who joined politics were imbued with the spirit of serving the nation. Those who plunged themselves into the fight for freedom knew that there were only sacrifices to be made, no return was expected. So only the selfless people came forward. But the modern politicians are of entirely different mould. They are not motivated by any lofty ideals. They win elections at a huge personal cost and then try to make the best of the opportunity they get. Powerful business magnates who are forced to give huge donations to political parties indulge in corrupt practices not only to make up their losses but also to consolidate their gains. Corruption in different fields Collusion is an agreement between two or more persons, sometimes illegal and therefore secretive, to limit open competition by deceiving, misleading, or  defrauding others of their legal rights, or to obtain an objective forbidden by law typically by defrauding or gaining an unfair advantage. Collusion is a corrupt activity. The different fields of corruption are 1. Political corruption 2. Police Corruption 3. Corporate corruption 4. Corruption in local Government 1. Political Corruption Political corruption is the use of legislated powers by government officials for illegitimate private gain. Misuse of government power for other purposes, such as repression of political opponents and general police brutality, is not considered political corruption. Neither are illegal acts by private persons or corporations not directly involved with the government. An illegal act by an officeholder constitutes political corruption only if the act is directly related to their official duties, is done under color of law or involves trading in influence. Forms of corruption vary, but include bribery, extortion, cronyism, nepotism, patronage, graft, and embezzlement. While corruption may facilitate criminal enterprise such as drug trafficking, money laundering, and human trafficking, it is not restricted to these activities. The activities that constitute illegal corruption differ depending on the country or jurisdiction. For instance, certain political funding practices that are legal in one place may be illegal in another. In some cases, government officials have broad or poorly defined powers, which make it difficult to distinguish between legal and illegal actions. Worldwide, bribery alone is estimated to involve over 1 trillion US dollars annually. A state of unrestrained political corruption is known as a kleptocracy, literally meaning â€Å"rule by thieves†. When people in power indulge in corruption so unabashedly, the common man gets a kind of sanction. Ironically, instead of  fighting against the menace of corruption, our political leaders declare it a worldwide phenomenon and accept it as something inevitable. 2. Police Corruption Police corruption is a specific form of police misconduct designed to obtain financial benefits, other personal gain, and/or career advancement for a police officer or officers in exchange for not pursuing, or selectively pursuing, an investigation or arrest. One common form of police corruption is soliciting and/or accepting bribes in exchange for not reporting organized drug or prostitution rings or other illegal activities. Another example is police officers flouting the police code of conduct in order to secure convictions of suspects — for example, through the use of falsified evidence. More rarely, police officers may deliberately and systematically participate in organized crime themselves. In most major cities there are internal affairs sections to investigate suspected police corruption or misconduct. Similar entities include the British Independent Police Complaints Commission. Police corruption is a significant widespread problem in many third world countries, such as Russia, Ukraine and Mexico. 3. Corporate Corruption Corporate crime refers to crimes committed either by a corporation (i.e., a business entity having a separate legal personality from the natural persons that manage its activities), or by individuals acting on behalf of a corporation or other business entity (see vicarious liability and corporate liability). Some negative behaviours by corporations may not actually be criminal; laws vary between jurisdictions. For example, some jurisdictions allow insider trading. Corporate crime overlaps with: †¢ White-collar crime, because the majority of individuals who may act as or represent the interests of the corporation are white-collar professionals; †¢ Organized crime, because criminals may set up corporations either for the purposes of crime or as vehicles for laundering the proceeds of crime. The world’s gross criminal product has been estimated at 20 percent of world trade. (de Brie 2000); and †¢ State-corporate crime because, in many contexts, the opportunity to commit crime emerges  from the relationship between the corporation and the state. 4. Corruption in Local Governments There are several types of political corruption that occur in local government. Some are more common than others, and some are more prevalent to local governments than to larger segments of government. Local governments may be more susceptible to corruption because interactions between private individuals and officials happen at greater levels of intimacy and with more frequency at more decentralized levels. Forms of corruption pertaining to money like bribery, extortion, embezzlement, and graft are found in local government systems. Other forms of political corruption are nepotism and patronage systems. Bribery Bribery is the offering of something which is most often money but can also be goods or services in order to gain an unfair advantage. Common advantages can be to sway a person’s opinion, action, or decision, reduce amounts fees collected, speed up a government grants, or change outcomes of legal processes. Extortion Extortion is threatening or inflicting harm to a person, their reputation, or their property in order to unjustly obtain money, actions, services, or other goods from that person. Blackmail is a form of extortion. Embezzlement Embezzlement is the illegal taking or appropriation of money or property that has been entrusted to a person but is actually owned by another. In political terms this is called graft which is when a political office holder unlawfully uses public funds for personal purposes. Nepotism Nepotism is the practice or inclination to favor a group or person who is a relative when giving promotions, jobs, raises, and other benefits to employees. This is often based on the concept of familism which believes that a person must always respect and favor family in all situations including those pertaining to politics and business. This leads some political officials to give privileges and positions of authority to  relatives based on relationships and regardless of their actual abilities. Patronage systems Patronage systems consist of the granting favors, contracts, or appointments to positions by a local public office holder or candidate for a political office in return for political support. Many times patronage is used to gain support and votes in elections or in passing legislation. Patronage systems disregard the formal rules of a local government and use personal instead of formalized channels to gain an advantage. Corruption Perceptions Index Since 1995, Transparency International (TI) publishes the Corruption Perceptions Index (CPI) annually ranking countries â€Å"by their perceived levels of corruption, as determined by expert assessments and opinion surveys.† The CPI generally defines corruption as â€Å"the misuse of public power for private benefit.† The results of the 2010 edition, as every year, are sobering. No region or country in the world is immune to the damages of corruption, the vast majority of them score below 5. The CPI has played a critical role in branding the issue of corruption on the world’s conscience. It sends a powerful message and national governments have been forced to take notice and act. The demand for public sector governance that keeps the interests of its citizens first with openness and accountability is not limited to a country or region – this is a common goal that transcends borders and cultures. The public sector is just one side of a multi-faceted problem though. Transparency International conducts an array of global research, such as the Global Corruption Barometer, a world wide public opinion survey, and the Bribe Payers Index, which measures the likelihood of firms from leading exporting countries to bribe abroad, which taken together enables us to better comprehend the many sides of corruption. Corruption is notoriously difficult to measure. The complexity and secrecy that shroud corrupt deals mean that it is virtually impossible to quantify the financial cost of corruption. The human expense is clear to see though, and it is the poorest that are most vulnerable. The diversity of victims that seek help from one of TI’s Advocacy and Legal Advice Centers shows that corruption can affect anyone. As we support these individuals, their personal triumphs are translated into systemic change – proving that corruption can be fought and  beaten. It may be that the CPI scores are just a number to you, but for many people around the world it is their daily reality. It need not be so. As Huguette Labelle, Chair of Transparency International, notes, â€Å"These 180 countries in our index are your countries, and their perceived levels of corruption will remain as such until you demand accountability.† India in Corruption Perception Index India’s ranking in Transparency International’s Corruption Perception Index too has slipped from 84 to 87 in 2010. All this exhibits a problem that is not going anywhere soon and mocks the high moral ground that we aspire to occupy in the international arena. Corruption has afflicted all the organs of our society including the polity, bureaucracy, judiciary, police, businessmen, and even public at large. It has rendered our governance apparatus hollow and ineffective. Countless efforts to combat corruption have not made any significant dent into this hydra headed monster. The public perception of India has been extensively damaged by the corrupt activities of politicians, bureaucrats and business houses. The telecom spectrum allocation scam – the biggest in the history of independent India – for which a minister, an MP and several corporate bosses are in jail and others are expected soon, the Commonwealth Games scandal in which the whole organizing committee, including the chairman are in jail, politicians grabbing prime real estate in housing Society meant for war widows in Mumbai, and the cash-for-vote scam involving parliamentarians have all badly eroded the public faith in government functioning in India. Corruption is silently eating into the vitals of our nation like termite. Bit by bit, it is denting our dignity and compromising our soul. Not only does it affect only individuals but alarmingly it affects our nation as a whole. India Against Corruption India Against Corruption (IAC) is a citizen’s movement to demand strong anti-corruption laws. Lokpal bills were introduced several times since 1968, yet they were never passed by the Indian Parliament. After a fast by veteran social activist Anna Hazare and widespread protests by citizens across India the Government of India constituted a 10-member Joint Committee of ministers  and civil society activists to draft an effective Jan Lokpal Bill. The primary focus of IAC movement is to ensure a strong Lokpal bill. This corruption in India does not lead simply to cabinet portfolio shifts or newspaper headlines, but to massive human deprivation and even more extreme income inequalities. Combating corruption in the region is not just about punishing corrupt politicians and bureaucrats but also saving human lives. The IAC is a strictly voluntary organization and its participants are bound by the IAC code of conduct. India Against Corruption Movement – Code Of Conduct 1. The movement is completely NONVIOLENT & PEACEFUL  2. It is INCLUSIVE & NON-DISCRIMINATORY. Encouraging every community regardless of religion, caste, language, region, culture, sex, age, profession, economic strata, etc. to be part of the movement and be treated equally. 3. The movement is completely SECULAR. Communalism is more dangerous than corruption. Also, the problems of this country cannot be solved without people from all faiths and religions coming together. 4. The volunteers should work in the spirit of SELFLESS SERVICE to fulfill the dream of realizing a strong Jan Lokpal Act for the country without expecting money, name, fame, recognition, etc. for oneself. 5. India Against Corruption is not a Sangathan or an NGO or any institution. It is a people’s movement, a collective expression of the people of India fighting against corruption and seeking a better future. Therefore, the movement cannot have any branches. Rather than an organizational structure, it seeks to develop an efficient communication structure to enable free flow of ideas. Every person participating in the movement does so as a citizen of India with a burning desire to do something for the country. No person is a representative of Anna Hazare or in any other position. 6. FRATERNITY & UNITY. People should work with a feeling of brotherhood and avoid conflicts within a group or across groups. The forces opposite us are so powerful. We must stay united if we have to win over them. Deficiencies in the present anti-corruption systems Central Government level: At central Government level, there is Central Vigilance Commission, Departmental vigilance and CBI. CVC and Departmental vigilance deal with vigilance (disciplinary proceedings) aspect of a corruption case and CBI deals with criminal aspect of that case. Central Vigilance Commission: CVC is the apex body for all vigilance cases in Government of India. †¢ However, it does not have adequate resources commensurate with the large number of complaints that it receives. CVC is a very small set up with a staff strength less than 200. It is supposed to check corruption in more than 1500 central government departments and ministries, some of them being as big as Central Excise, Railways, Income Tax etc. Therefore, it has to depend on the vigilance wings of respective departments and forwards most of the complaints for inquiry and report to them. While it monitors the progress of these complaints, there is delay and the complainants are often disturbed by this. It directly enquires into a few complaints on its own, especially when it suspects motivated delays or where senior officials could be implicated. But given the constraints of manpower, such number is really small. †¢ CVC is merely an advisory body. Central Government Departments seek CVC’s advice on various corruption cases. However, they are free to accept or reject CVC’s advice. Even in those cases, which are directly enquired into by the CVC, it can only advise government. CVC mentions these cases of non-acceptance in its monthly reports and the Annual Report to Parliament. But these are not much in focus in Parliamentary debates or by the media. †¢ Experience shows that CVC’s advice to initiate prosecution is rarely accepted and whenever CVC advised major penalty, it was reduced to minor penalty. Therefore, CVC can hardly be treated as an effective deterrent against corruption. †¢ CVC cannot direct CBI to initiate enquiries against any officer of the level of Joint Secretary and above on its own. The CBI has to seek the permission of that department, which obviously would not be granted if the senior officers of that department are involved and they could delay the case or see to it that permission would not be granted. †¢ CVC does not have powers to register criminal case. It deals only with vigilance or disciplinary matters. †¢ It does not have powers over politicians. If there is an involvement of a politician in any case, CVC could at best bring it to the notice of the Government. There are several cases of serious corruption in which officials and political executive are  involved together. †¢ It does not have any direct powers over departmental vigilance wings. Often it is seen that CVC forwards a complaint to a department and then keeps sending reminders to them to enquire and send report. Many a times, the departments just do not comply. CVC does not have any really effective powers over them to seek compliance of its orders. †¢ CVC does not have administrative control over officials in vigilance wings of various central government departments to which it forwards corruption complaints. Though the government does consult CVC before appointing the Chief Vigilance Officers of various departments, however, the final decision lies with the government. Also, the officials below CVO are appointed/transferred by that department only. Only in exceptional cases, if the CVO chooses to bring it to the notice of CVC, CVC could bring pressure on the Department to revoke orders but again such recommendations are not binding. †¢ Appointments to CVC are directly under the control of ruling political party, though the leader of the Opposition is a member of the Committee to select CVC and VCs. But the Committee only considers names put up before it and that is decided by the Government. The appointments are opaque. †¢ Therefore, though CVC is relatively independent in its functioning, it neither has resources nor powers to enquire and take action on complaints of corruption in a manner that meets the expectations of people or act as an effective deterrence against corruption. Departmental Vigilance Wings: Each Department has a vigilance wing, which is manned by officials from the same department (barring a few which have an outsider as Chief Vigilance Officer. However, all the officers under him belong to the same department). †¢ Since the officers in the vigilance wing of a department are from the same department and they can be posted to any position in that department anytime, it is practically impossible for them to be independent and objective while inquiring into complaints against their colleagues and seniors. If a complaint is received against a senior officer, it is impossible to enquire into that complaint because an officer who is in vigilance today might get posted under that senior officer some time in future. †¢ There have been instances of the officials posted in vigilance wing by that department having had a very corrupt past. While in vigilance, they try to scuttle all cases against themselves. They also turn vigilance wing into a hub of corruption, where cases are closed for  consideration. †¢ Departmental vigilance does not investigate into criminal aspect of any case. It does not have the powers to register an FIR. †¢ They also do not have any powers against politicians. †¢ Since the vigilance wing is directly under the control of the Head of that Department, it is practically impossible for them to enquire against senior officials of that department. †¢ Therefore, , the vigilance wing of any department is seen to softpedal on genuine complaints or used to enquire against † inconvenient† officers. CBI: CBI has powers of a police station to investigate and register FIR. It can investigate any case related to a Central Government department on its own or any case referred to it by any state government or any court. †¢ CBI is overburdened and does not accept cases even where amount of defalcation is alleged to be around Rs 1 crore. †¢ CBI is directly under the administrative control of Central Government. †¢ So, if a complaint pertains to any minister or politician who is part of a ruling coalition or a bureaucrat who is close to them, CBI’s credibility has suffered and there is increasing public perception that it cannot do a fair investigation and that it is influenced to to scuttle these cases. †¢ Again, because CBI is directly under the control of Central Government, CBI is perceived to have been often used to settle scores against inconvenient politicians. Therefore, if a citizen wants to make a complaint about corruption by a politician or an official in the Central Government, there isn’t a single anti-corruption agency which is effective and independent of the government, whose wrongdoings are sought to be investigated. CBI has powers but it is not independent. CVC is independent but it does not have sufficient powers or resources. Conclusion We are all part of this historic movement to eradicate corruption. Together, under the leadership of Anna Hazare, the â€Å"Jan Lokpal Bill† – a strong law to ensure swift and certain punishment to the corrupt political leaders and government officials is being drafted. Jan Lokpal Bill is a Law being made by the people and for the people. The success of this campaign depends entirely on us. So we have to support the fight for effective Jan Lokpal Bill. References http://www.google.co.in/ http://www.wikipedia.org/ http://www.indiaagainstcorruption.org

The Internet and the Role it plays in the Lives of Consumers and Term Paper

The Internet and the Role it plays in the Lives of Consumers and Businesses - Term Paper Example line Advertising 13 The Ability to Purchase Goods and Services at any Time 14 Timely Customer Service 14 Announcements and Promotions 14 Improved Bargaining Power for Customers 15 Share Experiences on Company Blogs 16 Disadvantages of the Internet for Customers 16 Conclusion 17 Bibliography 18 The Internet and the Role it plays in the Lives of Consumers and Businesses What is the Internet? According to Shuman (2001), it is gradually becoming more and more difficult to reach a consensual working definition of what exactly is the internet. However, it can broadly be defined as a worldwide interconnection of thousands of separate computer networks. The Internet was originally developed in the 1960’s in the United States and it was intended to help link the country’s government agencies with various universities and colleges. However, the internet’s real expansion was first witnessed in the early years of the 1990’s when thousands of different companies as wel l as millions of individual persons realized that they could actually be able to easily afford the necessary telecommunication technology as well as the graphic browsers that are found to be vital in securing access to the internet as well as exchanging messages (Oggerino, 2001). Since its introduction, the internet has played a strategically vital role in revolutionizing communications and computers. The internet is found to serve multiple roles by acting as a mechanism through which information can be disseminated, a vast and intricate world-wide broadcasting capability as well as acting as a medium that allows interaction and collaboration between various computers and the individuals operating them all over the world regardless of their present geographical location (Betz, 2011). The Internet is widely...These benefits are seen to range from reduced advertisement costs for businesses, large market share and penetration to making it easier for business organization in general to be able to carry out cheaper and more effective market surveys. Customers are also able to experience several key benefits that are seen to result from the role played by the internet such as it is now relatively easier for customers to be able to make various purchases from their homes, they are also able quickly compare the price of a given commodity between different stores before making a purchase a factor which makes them gain more bargaining power. However there are several innate disadvantages that have been seen to affect both customers and businesses as a result of the role that the internet is seen to play. Some of these disadvantageous roles that are played by the internet are seen to include, increased risk of identity theft on the part of the customers and the common fact that business enterprises and especially so those in the entertainment industry are finding it increasingly difficult to adequately safeguard their intellectual properties (Fatayerji, 2004). Regardless of the specific role that the internet has been seen to have played that has impacted either customers or businesses, it’s continuous and general influence cannot be ignored and it is important for all business organizations and customers to ensure that they continuously evaluate it so as to effectively determine any advantages they stand to reap or the potential dangers resulting from the role played by the internet.

ADVENTURE TOURIM Essay Example | Topics and Well Written Essays - 3000 words

ADVENTURE TOURIM - Essay Example Due to the element of surprise and risk, the challenges and the testing of the limits of the participants it involves, it has been gaining popularity, as the unusualness of the holidays rather than the typical vacations has been appealing. Adventure tourism is rapidly growing in popularity as tourists seek unusual holidays, different from the typical beach vacation. Adventure tourism may be a combination of travelling into generally involves travelling into remote, inaccessible and possibly hostile areas. It may require a certain minimal level of physical fitness and courage and determination to go through with the tour. (Source from website http://en.wikipedia.org/wiki/Adventure_tourism) Adventure Travel may be â€Å"hard† with high levels of risk, requiring intense physical fitness and greater skills, like climbing Mt. Everest or white water rafting in rapids. It can be â€Å"softâ€Å" with a perceived risk but actually â€Å"doctored† levels of real risk requiring minimal commitment and low skill level often insulated by supervision from experienced guides like hot air ballooning or hang gliding. There are different types of these tours with subtle differences. Eco tours are often undertaken in small groups and try to be conducted with minimal impact to the environment and the local community. They may be soft or hard adventures often accompanied by a tour guide well versed in native geographies. Some of them aim to be educational. Nature-tourism involves interaction with nature for observation and recreation. More holidays, more disposable income and more transportation options have encouraged people to get out more. Vacations have become a necessity to get away from the fast paced life. Added to this health consciousness has risen among today’s societies and the incentive to be healthy and fit has encouraged the love of the

Answer 11 questionsthis is not an essay Assignment

Answer 11 questionsthis is not an essay - Assignment Example The dance was introduced in 1953 by a Cuban violinist called Enrique Jorrà ­n. This dance has split fourth beat. A person begins the dance by starting with the second beat. Enrique also introduced this dance style in London, and it is currently referred to as the ballroom cha-cha (Andrews 7). 3. The rumba music started in Cuba as an integration of many musical practices. Rumba in Cuba is played through both the triple-pulse and the double-pulse structures (Andrews 3). Rumba is rhythmically played using the five-stroke system referred to as clave. The current types of rumba are; Columbia, yambu and guaguanco. The three rumba types are unique, due to different choreography. 4. Samba refers to a Brazilian dance. The dance style originated in Brazil; however, it has African roots which were influenced through slave trade. The Bahian Samba dance is currently a UNESCO Heritage is Humanity (Andrews 10), and it is mostly played in Rio de Janeiro. The samba is traditionally played by various percussion and guitar types. On 2nd December ever year in Brazil, celebration of the Samba National day is held. 5. Carlos Santana is a Mexican American musician, who was very famous in the 1960s and 1970s. His Santana band initiated the integration of Latin American music with rock music. He has won numerous music awards; for example 10 Grammy awards (Andrews 15). The guitar lines of Carlos were usually based on the African and Latin rhythms. His popularity in the world music industry was again felt towards the end of the 1990s. 7. The Andean music ensemble is currently a music type with global audience because; native sounds of the music has been continuously mixed with music form applicable to modern and middle class Europeans. 8. Peruvian wayno is a popular type of Andean music common in Peru, Chile and Argentina. It is performed by various ethic groups, for example the Quechua and the Aymara societies. Its superior character

The lottery Research Paper Example | Topics and Well Written Essays - 1000 words

The lottery - Research Paper Example They are to pick a paper from the black box and whoever picks the black marked paper is doomed to die. The story narrates that Mr. Hutchinson picked the marked paper so that out of all the villagers, each member of his family was to pick from the box to determine who will finally suffer the consequences of the tradition. Tessie Hutchinson, the wife, picked the marked paper and therefore was stoned to death. This may be very barbaric but â€Å"The Lottery† speaks more genuine concerns about tradition and how people treat it, than it looks to be in this retelling of the story. It also portrays literary elements such as point of view, setting, characters, plot and role of tradition in the story which will be discussed in detail in this paper. â€Å"The Lottery† is told by a third person narrator (Cencage) whose view of the characters is limited. The storyteller is not able to tell the thoughts of the characters but efficiently narrates the story by simply identifying the c haracters and describing them, their actions or their words and facial expressions. Cencage describes the manner of narration as â€Å"detached and objective† in recounting the events of the story. ... here the story was set, this day could be seen as a day when children would go out and play gleefully outside or it would be a wonderful day for families to go walking together or have a picnic in the park. According to Cencage, the 27th could a day when the solstice, the longest day of the year, occurs. It is said that traditionally, people sacrificed humans during the solstice and so the significance of this in the story cannot be easily dismissed as it soon eventually unfolds in the story that the winner of the lottery is going to be stoned to death. In an interview with the author, she was asked about how she came up with the story and she comments, â€Å"Perhaps the effort of that last 50 yards up the hill put an edge on the story. It was a warm morning and the hill was steep† (nothbennington.org). However, behind the setting are also characters which made the story come alive. The narrative presents most of the villagers as a group and they are not identified. There are many minor characters which have been mentioned and there are also major players. However, this paper will focus on one major character, Tessie Hutchinson, who unfortunately picked the doomed marked paper that led to her death. Mrs. Hutchinson is first seen in the story running from her home, still on her house clothes. Evidently, she has been doing her household chores and has hurried to the meeting to participate in the lottery that was about to take place. She is also presented as a happy and talkative person who easily speaks her mind and feelings. However, when she â€Å"wins the lottery and is stoned to death by her fellow villagers† (Cencage), Tessie finds the courage to rally herself against the fairness of the system and the tradition. Tessie is the symbol of the rise of feminism. In a

Do we think for ourselves or does society determine what we think (the Essay - 1

Do we think for ourselves or does society determine what we think (the social construction of reality) - Essay Example Society determines us; the life of an individual and how he/she thinks is determined and moulded by the society the individual lives in: this form the thesis of my paper. An analysis of different stereotypes and concepts will be carried out to help prove this statement. A critical society is one with individuals who value critical thinking as well as value those who are practicing it.   Its most distinguishing feature is that it stresses on thinking as central to the emancipation of mind, to the development and preservation of the species and to the establishment of just practices. Unfortunately, no critical society exists in the world.   The concept represents an ideal that is yet to be achieved and actualized.   However, there are some professions and culture on earth in which critical thought is the characteristic of everyday social and personal life. The world is occupied by superficiality, bias, prejudice, distortions, manipulation, lies, deception, short sightedness, hypocrisy, close-mindedness, righteousness, on and on, in each culture in every part across the world.   These problems in our thinking occasion untold negative implications such as fear, sadness, anxiety, hopelessness, suffering, pain, injustices of every thinkable kind. People have an incredible capacity for reasonability and rationality.   The history of our accomplishments, achievements and contributions, initiated and shaped by our society well documents this fact.   Nonetheless, for the better part, this capacity should be actively developed by the mind.   It is our second nature determined by our society. What is more natural to our mind, whatever comes first concerning human tendencies, and habitually takes priority, is an orientation emphasized on self-gratification, self-protection and self-interest.   This perspective is inborn, and most people would say it`s necessary for survival. To visualize that our societies are critical

How technology today affects a student's success Research Paper

How technology today affects a student's success - Research Paper Example The technological devices, including simple tool-based applications, video devices, online repositories, computers and handheld devices, have found wide application in various learning institutions and among students across the globe. Thus, this research paper aims at analyzing how technology has caused students to experience success through accessibility of materials, choice of convenient learning styles and enhancement of technological proficiency. Technology makes learning materials available to students, thus greater access, which increases the body of knowledge from which students learn from. Web browsers provide students with opportunities to find information on whatever subject. In fact, they provide more current materials than most school libraries do (Gemmill, and Peterson 281). Among the materials that students stand to benefit from the Internet include up-to-date tutorials and research papers. Software tools like spreadsheets, concept maps and databases allow these student s to organize and evaluate whatever data they access online. In addition, the accessed materials teach students to create work that depicts a high sense of professionalism, thus expanding the knowledge of such students. Another important information which technology, particularly the Internet, provides include comparison information on various learning institutions (Rambe 272). When seeking for an institution that would meet a student’s needs, it would be critical to get information on the various available options. The Internet provides information on the location, specialties and fees structure of such institutions. Furthermore, the global rankings of such institutions help students make informed choices of which institution to join. Rightful decisions enhance the desirable performance among students. Secondly, technology provides more convenient learning approaches which make learning comfortable and consequently boost students’ concentration in academics. In classr ooms, many teachers have adopted digital media to foster students’ skills. According to (Muir-Herzig 114), teachers use technological applications to simulate real-world phenomena to enable students execute authentic assignments as real workers would. Audio and video technology stimulates young minds which facilitates learning. The incorporation of pictures, animation and sound makes multimedia enhance recalling of basic facts among students as well as enhancing their understating of systems considered to be complex. Technology allows for learning in an institution of choice from whatever location in the world through distance learning which enables students to learn conveniently. The constructivist learning and teaching model cited by Muir-Herzig (114) indicates that due to the complexity of tasks brought about by technology, students’ motivation to learn increases. For example, as observed from a study by Gulek and Demirtas (29), students using laptops engage more in collaborative work than those without and further get motivated in writing their assignments, producing high quality work of greater length. They explore topics on their own, spending more time working on their school projects. The collaboration with other students through appropriate platforms such as social media enables students to tap into the available opportunities (Rambe 272). Whatever the preferred mode of learning, students leverage on technology to

Sub-human working conditions in Qatar Research Paper

Sub-human working conditions in Qatar - Research Paper Example The world cup is the most widely viewed sports event in the world and requires a lot of preparation by host countries to be in a position to stage the world cup owing to the high number of spectators, reporters, business people, and players who come to the host country for the world cup. Qatar has been making these preparations since 2010 when it was selected to host the 2022 world cup but there are rampant cases of inhuman working conditions for workers making preparations in stadia and other facilities in the country. It is from this understanding that this study aims at enumerating why FIFA and football associations should force Qatar to stop the "sub-human" working conditions. Workers involved in infrastructure development for the 2022 world cup are exposed to harsh working conditions including withheld payments, working in 122-degree heat for a long time with no provision of food or water, and their passports were confiscated to ensure they do not leave the country (Kwok & Wallis, 2008). Workers cannot be able to help their families and pay obligations for their jobs to recruitment agencies with 36% interest payment rates affecting their families and their person negatively (Manfred, 2014). For a country that will host the world cup, these conditions are unacceptable owing to the high benefits to be received by the country and the high following that the world cup has globally. This will taint the name of the world cup and FIFA, if the football associations and FIFA do not take the steps to correct the situation in Qatar in terms of working conditions. The intolerable working conditions in Qatar have led to the death of at least 1200 workers in different infrastructural development in preparation for the world cup with 400 of them from Nepal, 00 from India, and others from Philippines, Pakistan, Kenya, and other parts of the world. This is in accordance to a report by The International Trade Union Confederation (Manfred,

Information security management framework Research Paper

Information security management framework - Research Paper Example Frameworks are based on existing standards that have been accepted as well as guidelines and sets of practices that reflect the conduct of an initial community of organizations that perform highly(HrÃŒÅ'ebiÃŒ cÃŒÅ'ek, Schimak&Denzer, 2011). Governments along with business organizations have an ability to implement frameworks with the practices they prefer or are supposed to use for their market sectors and the entire country. Some of the benefits of possessing frameworks for information security management include the fact that they create a secure and well-arranged working environment while at the same time protecting information and information assets. Having frameworks for information security management also assists in the reduction of internal and external breaches in security, creating confidence among the employees and customers when dealing with the operations of the business and integrating recovery from disasters in order to ensure continuity of the business(Gantz&Philpott, 2013). Further benefits include prevention of information security incidences from taking place and detection of incidences from occurring. In the event that incidences take place, the frameworks for information security management are able to measure the impact of the incidences and respond to them in order to minimize the resulting damage. Additionally, they are able to embed continuous improvement in processes associated with information security while complying with rules and regulations. Information security frameworks are a sequence of standard procedures that are employed in defining policies and processes associated with the execution and continuous running of information security controls in an venture setting. The frameworks are essentially a plan for the creation of an information security plan with the aim of managing risks and reducing any vulnerability. Professionals in information security can employ

The Old proof of Human Craving to Preserve Heritage Essay Example for Free

The Old proof of Human Craving to Preserve Heritage Essay Humans love their routes and even more love to bask in the glory of the accomplishment of their ancestors, and such attitude towards heritage has only manifested in modern times with the advent of museums. However, the level of wonder rises to an unbelievable degree when one discovers a piece of architecture as old as 421 BCE too clearly consolidates the above belief. That is the reason why this essay has chosen to describe Erechtheion, the building that was decidedly built to accommodate all possible nuances of ancient Greek heritage and culture. Background Right after they completed Parthenon and the Propylaia, the city-states of Athens and Sparta and their respective allies got involved in the Peloponnesian Wars between 431 and 404 BCE, between which they had a peaceful period of six years under the regime of Nikias, and the Athenians didnt miss that chance to fulfil the dream of their dead hero Perikles (died in 429 BCE), who wanted to restore the glory of Acropolis, and accordingly started constructing Athena Polias, which later became known as the Erechtheion (Syrigos, 1995), the work of which commenced on 421 BCE and finished around 406 BCE. Erechtheion contains six larger than life maidens columns known as the Caryatids. According to mythology, it was here that Poseidon struck the ground with his trident and that Athena produced the Olive tree. Overall, the building proves to be a brilliant solution of both spiritual confluence and practical problems (Sanctuary, 2006). Architectural Details The Erechtheion had two main entrances, on the north and east sides, where some columns from the east porch, comprising an ornamental pedestal supporting a fluted shaft of white marble and topped by a separately made capital, carried the flavour of neo-classical architecture, especially with their floral ornament of the necking and the delicate mouldings of the pedestal and capital (Cook, 1997). The uniqueness of this building lies in the fact that it contains more original features than any of its counterparts in Acropolis. It can be classified by three separate independent sections like the central temple, the porch of the Caryatides and the north extension, all having separate roofs. Apart from that, it is built at four different levels and accordingly, Ionic columns of three different dimensions and proportions are used, besides Korai as supports for the entablature the famous Caryatides (Erechtheion, 2008). Otherwise the temple has two main parts, where once Athena reigned at the east and Poseidon-Erechtheus found their places at the west. In all, it reflected the compactness of classical Attic architecture. The frieze was created out of Eleusinian stone of a deep grey colour, and metal connecting pins set in the slabs were used to hold the relief figures. Once a gold lamp adorned inside, reportedly made by Kallimakhos, the artist accredited with the invention of the Corinthian capital (Syrigos, 1995). There is no authentic document regarding the architect of this building, yet its Ionic structure would remind the genius of Mnesikles, who is regarded as one of the stalwarts of Greek architecture and who was known for his originality and his ability to provide functional adaptation to accommodate the multiple religious needs of so many cults, even amid the irregular basement (Syrigos, 1995). Another researcher Williamson (2008) too supports this idea, who opines, The Erechtheion, built on the site of ancient sanctuaries on the Athenian Acropolis, is so unlike every other Greek temple that some have dismissed it as an aberration. Rather, it is the result of its architect, probably Mnesikles, applying inventive skill to accommodate a complex web of religious relationships. The Erechtheion provides evidence that the craft tradition of architecture, hobbled by convention, was giving place to a new creative approach to design. Proof of Craving to Preserve Heritage It is this meticulous projection of religious confluence of Greece separates Erechtheion in dignity, as it comprehensively covered the spiritual milieu of ancient Greece within its chambers and its temenos (sacred courtyard). Though the structure primarily facilitated worship of Athena Polias and Poseidon, it meticulously accommodated a host of other important characters/elements of Greek Mythology, like the graves of Erechtheus with the sacred snake, and of Kekrops, the ancestors of the Athenians, as well as the signs from Poseidons trident which produced water, the Erechtheis Sea, a well that contained salt water, and the marks from the thunderbolt of Zeus. The altars of Zeus Hypatos, of Peseidon and Erechtheus, of Hephaistos, of the hero Boutes, of the Thyechoos, and the very ancient xoanon of Hermes, all were placed together there. And there was more the sacred olive and the sanctuary of Pandrosos, which included the altar of Zeus Herkeios too found their places (Sanctuary, 2006). According Syrigos (1995), the architect succeeded by subtle and ingenious use of the differences in level to produce an astonishing temple, which satisfied the requirements of all these cults. He respected the traditions and at the same time introduced striking innovations. Present Situation The unique temple was converted into a church during the Middle Ages, and later it was used as a harem for the ruler of Athens during the Turkish occupation. In 1801 the British ambassador, Thomas Bruce, Earl of Elgin, took a caryatid (which he later sold to the British Museum), replacing it with a plaster cast. The Erechtheion was partly rebuilt by the American School of Classical Studies. Now it again suffers depredations, this time from atmospheric pollution and the increasing pressure of tourism (Williamson, 2008). Conclusion The evidences and discussion clearly points at the innate desire of the Greeks to preserve their heritage at one place, and the intensity of such desire brought the issue completing their mammoth task of creating Acropolis even after the war, which normally could be a period of general consolidation. Thus, apart from skill, innovativeness and beauty, which are tangible in Erechtheion, one intangible proof is right there, which proves human craving fore preserving their heritage and gather inspiration from it. References Cook, B. F. (1997). Ionic column from the ErechtheionThe Acropolis, Athens, Greece, about 420-415 BC in The Elgin Marbles. 2nd Edition: London, The British Museum Press. Retrieved 8 December 2008, from http://www. britishmuseum. org/explore/highlights/highlight_objects/gr/i/ionic_col umn_-_the_erechtheion. aspx Erechtheion (2008). Retrieved 8 December 2008, from http://www. erechtheion. org/Docs/Lesk%20Erechtheion%20with%20figs%20sm. p df http://www. ne. jp/asahi/daikannw/network/webacropol/erechtheio. html Sanctuary of Erechtheion. (2006). Retrieved 8 December 2008, from http://www. travelpod. com/travel- photo/rcl0906/turkey_greece06/1158590880/dscn03. jpg/tpod. html Syrigos, A. B. (1995). The Erechtheion. Retrieved 8 December 2008, from Williamson, M. (2008). The Erechtheion, Athens, Greece; Mnesikles(? ), architect, 421- ca. 406 b. c. Retrieved 8 December 2008, from http://warandgame. blogspot. com/2008/08/erechtheion. html

Challenges Caused by the Knowledge Economy

Challenges Caused by the Knowledge Economy With reference to the concept of the corporate curriculum, how far do you consider an organisation with which you are familiar to be meeting the challenges presented by the knowledge economy? Introduction: With the emergence of the new knowledge-based economy, organisations are slowly starting to see a new need to apply knowledge management practices and principles to their corporate curriculum. In todays competitive landscape, organisations must develop different capabilities and strategies in order to meet the demands of the knowledge economy. In order to do this, firms must be able to effectively deploy, utilize and manage knowledge. Knowledge management can be harnessed to foster learning in the organisation. It is also important to identify and use knowledge through strategic capabilities, knowledge productivity, and corporate curriculum. Managers of today should think critically about the use of learning and knowledge processes in order to be successful. Increasing globalization, continuous improvements in technology and growing competitiveness of the different industries around the world are just some of the pressures which are forcing some organisations to streamline their business processes and utilize not only their traditional and competitive resources but also their collective knowledge. Every organisation survives in an atmosphere that conditions the way the organisation carries out its business. There are business drivers that have influenced how organisations behave towards knowledge management. The airline industry as a member of the professional services sector recognizes knowledge as a product, people as primary source, mobile workforce and mergers are some of its key business drivers (Abel and Oxbrow, 2001). Learning and Knowledge Management There are many ways to define knowledge management as much as there are a lot of approaches to implementing it and using it. In the context of learning, Alavi and Leidner (2001) describe knowledge management as a dynamic and continuous organisational phenomenon that involves distinct but interdependent processes of knowledge creation, knowledge retrieval, knowledge transfer, and knowledge application. Ponniah (2001, p. 54) defines knowledge management as a systematic process for capturing, integrating, organizing, and communicating knowledge accumulated by employees. He further describes it as a vehicle to share corporate knowledge so that employees may be more effective and be productive in their work. In every organisation, innovation or learning occurs as a result of the flow and transformation of knowledge and other intellectual assets. Accordingly, innovation, whether reorientation or variation, is a reflection of the internal organisational positioning of the firms innovative unit, the character of technological interdependencies in a particular innovation, and the character of knowledge and technological interdependencies (Goodman and Lawless, p. 240). According to Andreu and Sieber (2001, p. 61), differences in knowledge led to differences in learning. For organisations, it is important to have a clear idea about what types of knowledge are present in individuals within the organisation. It is also important for organisations to incorporate relevant knowledge from the environment so that they are capable of offering to potential clients whatever becomes standard in the marketplace. Nonaka (1991) says there is another way to think about knowledge and its role in business orga nisations. He cites as examples some Japanese companies like Honda, Canon, and Sharp. He says that managers of these firms tap on the tacit and often highly subjective insights of employees which often results to a spiral of knowledge at continuing higher levels and it is not simply the processing of factual information. As organisations grow, the level of learning and the quality of knowledge becomes more important and critical to the business inputs and processes. Andreu and Sieber (2001) support this fact by saying that it is the interaction of individuals in a group and therefore the collective character of work in organisations that gave rise to the concept of organisational learning. It is also through organisational learning that organisations are beginning to see the impact of using intellectual assets as another means to fight their way out of the doldrums. Challenges of the Knowledge Economy The information age is marked by the rise of mass customization, dynamic processes, virtual organisations, and a whole set of new practices and administrative structures enabled by global communications and information systems (Meadows et al, p. 38). The essential resources to consider in todays knowledge economy therefore are knowledge, labor, and organisational capabilities (Meadows et al). In an economy that is becoming increasingly driven by new shifts in technology and competition, it is no longer possible for traditional organisations and industries of today to concentrate on their static assets. They must constantly move their resources and adjust to certain communications structures, management practices, personnel development, and sales and marketing strategies. The increasing rates of change, increasing global competition, a more diverse workforce, a more demanding and satisfaction-conscious customers are just some of the challenges that organisations are facing today as they make a transformation from an industrial organisation to a knowledge-based organisation. The greater challenge however lies on how to use knowledge in order to bring out innovative ideas and create more value for the organisation and trigger product and services differentiation. The Corporate Curriculum For an organisation to meet the challenges presented by the knowledge economy, learning and development should be incorporated in the overall corporate plan and business process. The organisation must adopt a corporate culture which integrates the transformation of the organisation using the available intellectual and the internal and external knowledge assets with the corporate development process. Formalized training programs should include a corporate curriculum plan match with the prevailing job and managerial skills of individual members of the organisation to the needs of the entire organisation. It should also provide an avenue for knowledge and the entire learning processes to flourish and help the organisation sustain its competitive edge. There should be programs for enhancing the strategic communication which would guide managers and employees on the how to communicate the mission-vision and the corporate strategy to different levels and departments of the organisation. It should also be able to skillfully impart its mission-vision and guiding principles to its members and clients as well. Programs should also showcase the effective management skills which come with the recruitment and selection process of employees, encouraging motivation, giving due and just compensation, providing coaching and training programs, and enhancing the performance management. Using human resources and learning methods for knowledge management purposes include knowledge management awareness and development of a knowledge sharing attitude and skills as part of a corporate curriculum (Efimova and Swaak). Leadership and personal development should be able to help define the dynamic character of a leader and enhance leadership styles and approaches suitable for the organisation and its environment. It should also help enhance team building activities and help and empower members of the organisation to take charge of their own career development. Sales and Marketing courses should help improve the negotiating and selling skills and market analysis and planning skills as well. Service Excellence should be able to make changes to certain strategies in order to improve customer satisfaction and allow room for a creative problem solving strategy. In this paper, Singapore Airlines (SIA) was chosen as the organisation of choice because the company operates in an emerging economy of Asia which offers an ideal situation in which to discuss the challenges encountered in an evolving knowledge economy. The company is also recognized as an innovation-based organisation that places strong emphasis on value creation through knowledge (Goh, 2005). Strategic Communication Large organisations like SIA take into account the importance of having good communication strategies in order to bring their messages across their members located in different cities and subsidiaries around the world. Kaufman says that SIA publishes a variety of newsletters and company-wide magazines on top of having regular dialogue sessions between management and staff. New suggestions are constantly heard and put forward in different business meetings which was then called Staff ideas in Action (Kaufman). This scheme ensures that feedback from front-line workers was taken into consideration when improving the delivery of services and products. Internal staff communication and information dissemination with employees is also encouraged through a variety of regular departmental meetings (Goh, 2005). These meetings provide the forum for further evaluation of sales, yields and customer satisfaction levels. Goh (2005) adds that over the years, SIAs technology strategy has involved hug e investments in many state-of-the-art technologies In order to strengthen its knowledge networks for predicting the demand and supply of airline seats. SIA deemed it important to use networked knowledge resource as a vital asset in optimizing the allocation of airline seats more effectively. If this networked knowledge is well managed, they are a good influence for pursuing further innovation based on superior performance. Knowledge is therefore best viewed as the catalyst for exploring innovative ideas which occur between and within organisations at knowledge exchanges due to stepped up transfer between knowledge communities. Nonaka (1991) therefore says that managing the knowledge-creating company requires the building of overlapping company information, business activities, and managerial responsibilities which encourages further communication and helps create a common ground for the transfer of open knowledge. In order to innovate effectively, organisations like SIA should also adopt knowledge management practices based on a collaborative knowledge strategy through symbiotic relationships by knowledge sharing. Todays knowledge-based environments require the assimilation of knowledge from diverse disciplines which can be drawn from a variety of fields of expertise. This often results to superior innovative products and practices. In a highly competitive environment such as the airline industry, success generally means that the provision of products and services before ticket purchase and after passenger arrival must be taken seriously. If we are to consider how SIA innovates on its strategic communication process, it is worth noting that SIA management greatly understands the value of constant feedback and the establishment of open communication channels with customers at all times, in any place, and in any situation as the best way to improve on its corporate competitiveness. SIA makes an intensive effort to stay in touch with customers by listening to hidden wants and needs and ensure rapid response to customer complaints. Effective Management Skills SIA is constantly challenged from almost all fronts. Even though its business model is often an envy of other industry players, theres still a lot of room for improvement. In here, SIA must respond by continuously creating new value for the market it serves. It has recently moved from resource allocation of physical assets towards the pursuit of knowledge innovation. This move has enhanced corporate competitiveness by using knowledge together with scientific, technological, organisational, and managerial assets. Managing knowledge is basically managing people (Goh, 2005). It must be made clear however that people-centered priorities are most crucial in a successful knowledge-based enterprise. Machines and technology are often proficient in gathering and performing information tasks. People are more involved in knowledge tasks. It is said that people are the real intelligent agents in knowledge management solutions regardless of how powerful and advanced the technology may be. People are the ones who can identify, assess, analyse, and act upon opportunities for learning brought about by the acquisition of new knowledge in order to help sustain the organisation. Kaufman says that training and other educational programs at SIA are not one-time affairs. SIA recognizes the changing customer expectations and the complexity in handling daily customer contacts can be an exhausting experience. One of SIAs competitive advantages has been its total commitment to talent. SIAs consistency in its training programs allows it to surge ahead in service quality (even during economic slumps) when its competitors are cutting back on training costs. It also demonstrates to all its members that continuous learning and improvement are essential principles for success, and not just for add-ons. Compared to the current industry standards, SIA goes to extraordinary lengths to attract, develop, and retain the best people by recognizing that only people who are trained with the right technological tools can intelligently assemble, interpret, and utilize knowledge for the purpose of servicing the advancement of the organisations innovation goals. Kleiman (1999) contends that training practices and skills development illustrates the commitment of management to constantly improve the skills of its personnel. By investing and incorporating these programs within the overall corporate curriculum, employees do not only get to have an avenue for career development and improve their skills and knowledge. They also bring in different forms of information and expertise (and knowledge) which can be potent weapons by the company in maintaining its competitive advantage. People are motivated to grow for a lot of reasons. First, it augments a persons human capital and labor market position. Second, it aligns the growth with deeper personal intrinsic motives (Wijnhoven, p.303). According to Wheatley (2000, p. 6), human needs and motivation lead us naturally to create knowledge. Studies confirm that people want their work to provide growth, recognition, meaning, and good relationships. We want our lives to mean something, we want to make contributions to society and to other people, and we want to continually learn and improve our skills. Inducing people to work in new ways for quality and innovation may also involve overcoming past habits, values, beliefs, and identity (Michela and Warner Burke, p. 234). Skyrme (2000, p.78) discovers that many companies do not reward people for sharing information. Management consultancies now include peoples contribution to their knowledge bases as part of their performance and salary review. At SIA, excellent staff performance is rewarded with increased pay and position. Individual innovation on how to respond to unique customer situations with exceptionally positive, innovative, or selfless acts of service is added knowledge to the company and is also aptly rewarded with increased pay and position. By empowering their employees and supporting decentralization of decision making and broader workforce participation, employees are usually given prominent roles in running the business. It also encourages greater responsibility for individual and group actions on decisions they make. Leadership and Personal Development Management suggests custodianship, control and a concentration on managing resources that already exist. According to Skyrme (2000), a better term for knowledge management is knowledge leadership. It is more about constant development and innovation of information resources and of knowledge and learning networks. It embraces both the sharing of what is known, and innovation which are the two thrusts of a knowledge-enhanced strategy. Successful knowledge innovations are not characterized by instruction-centered production tasks, and corporate leaders should reduce top-down structures that hinder productive knowledge processes (Goh, 2005). The traditional hierarchy structure and style of management is often seen as detrimental to a knowledge generating culture. In SIAs management hierarchy, managers always have time to listen to employee feedbacks and these feedbacks are valued at every level of the hierarchy. In the concept of a knowledge-based economy, everybody is considered a knowledge worker (Wheatley, 2000). If everybody is assumed to be creating knowledge, then the organisation has a responsibility to provide open access to information to everyone. It is therefore assumed that knowledge will be found everywhere in the organisation, not just in a few places or levels of the organisation. At SIA, the staff is regularly evaluated for performance and potential (Kaufman). Senior managers are frequently rotated within the top positions of the company. The management team is described as having a shared understanding of the big picture due to the great breadth and depth of their experience and reach within the company. Collaboration and team building is closely evidenced by the fact that SIAs products, services, and solutions are heavily invested in order to foster a strong knowledge-sharing culture (Goh, 2005). The introduction of web-based technologies and a company-wide focus on developing team-based competencies to improve the companys capabilities in knowledge collaboration also support the personal development of the organisation. Sales and Marketing According to Kaufman, SIA keeps track of their competitors progress closely while keeping an open eye for new ways to improve and grow. Whenever other service industries (like hotels, banks, and restaurants) take steps forward in their amenities and comfort, SIA takes the initiative to analyse and study innovative ways in which it can leverage and adopt these existing opportunities for their customers satisfaction. To address customer demands, SIA developed a quarterly Service Performance Index that provides a consolidation of statistics relating to customer service (Goh, 2005). This index is closely monitored globally and benchmarked against the service standards of leading airline competitors in the Asian region. SIA also undertakes an environmental scan on consumer trends of competitors and other similar services. Service Excellence In a new knowledge-based economy, clients are more informed and more perceptive and sensitive of their needs and wants. To ensure that these clients new needs are met, knowledge-based organisations should be more customer-centric. At SIA, its strategic centerpiece is on ensuring that customer get the best deal and value on every deal that it makes with its stakeholders. Conclusion: The success of knowledge innovation depends on members of the organisation who utilized the knowledge and not the knowledge itself. In order for an organisation to succeed and sustain its competitive advantage, organisations should have a formal and knowledge-friendly environment where it can promote and cultivate a knowledge-oriented culture and knowledge-driven management and personnel programs. Singapore Airlines is known as one of the best airlines in the world in terms of customer satisfaction and ability to weather the onslaught of new competitors. In general, SIA is faring much better than its competitors because it has consistently aligned its strategic goals and innovation investments with a collaborative knowledge strategy. SIAs technology strategy involved modern technology to strengthen its knowledge network. It has a people-centered philosophy by training and developing its people in order to have knowledge workers in their ranks. SIAs hierarchical management style is st ructured to encourage and value feedback from different levels of the organisation. To meet the challenges of knowledge economy, SIAs corporate curriculum offer a wide range of inspiring and demanding educational programs that continually motivate, upgrade, and improve their employees and managers performance. The main reason why SIA has continually flown on both wings on the sky is that it has found good ways and means of using an intangible asset in the form of knowledge to fuel their drive towards customer service perfection. Bibliography Abel, A and OxBrow, N (2001), Competing with Knowledge, Library Association Publishing, London. Garvey, B and Williamson, B (2002), Beyond Knowledge Management: Dialogue, Creativity, and the Corporate Curriculum, Pearson Education, Harlo, UK. Goodman, R and Lawless, M (1994), Technology and Strategy: Conceptual Models and Diagnostics, Oxford University Press, New York. Kleiman, L (1999), Human Resource Management: A Managerial Tool for Competitive Advantage, 2nd edn. Ponniah, Paulraj (2001), Data Warehousing Fundamentals, John Wiley and Sons, Canada. Andreu, R and Sieber, S (2001), Organisational Learning and Knowledge Management: Where is the link?, Malhotra, Y (ed), Knowledge Management and Business Model Innovation, Idea Group Publishing,London. Meadows, C et al (2001), Building a Competitive Advantage in the Knowledge Economy,Malhotra, Y (ed), Knowledge Management and Business Model Innovation, Idea Group Publishing, London. Michela, J and Warner Burke W (2001), Organisational Culture and Climate in Transformations for Quality and Innovation, Ashkanasy, N et al (eds), Handbook of Organisational Culture and Climate, Sage Publication, London. Skyrme, D (2000), Developing a Knowledge Strategy: From Management to Leadership, Morey, D et al (eds), Knowledge Management: Classic and Contemporary Works, MIT Press, London. Wijnhoven, F (2001), A Framework for Stakeholder-Based Knowledge Valuation in Organisations, Malhotra, Y (ed) Knowledge Management and Business Model Innovation, Idea Group Publishing, London. Efimova, L and Swaak, J (2003), Converging Knowledge Management , Training, and e-Learning: Scenarios to make it work: Proceedings of I-Know 03, Graz, Austria, July 2-4, 2003, Retrieved: February 21, 2006 from i-Know-center online database. Kaufman, Ron (n.d), How Does Singapore Airlines Fly So High? Retrieved last February 21, 2006 from Abel, A and OxBrow, N (2001), Competing with Knowledge, Library Association Publishing, London.

Ethosomal Formulation as a Carrier for Transdermal Delivery

Ethosomal Formulation as a Carrier for Transdermal Delivery ABSTRACT: The aim of present work was to develop, characterisation, of stable ethosomal formulation as a carrier for transdermal delivery of paroxetine hydrochloride. To prepare this ethosome different concentration of soya lecithin and ethanol was taken. Vesicular size, polydispersity index, zeta potential, entrapment effiency were determined by photon correlation spectroscopy and ultracentrifugation techniques. The intro permeation study across human cadaver skin was done. Stability study was done on optimised F2 formulation. Vesicle size decrease as increase in the concentration of ethanol. Entrapment efficiency increase with increase in concentration of soya lecithin. The ethosome exhibit entrapment effiency of 40-64%. Invitro permeation study across human skin ethosome F2formulation showed higher transdermal flux 26.39% µg/cm2/hr. Release mechanism of Invitro permeation shows zero order drug release from formulation. In vivo pharmacodyanamic study F2 formulation showed significant immob ility as compare to controlled group. Stability study result revealed no significant change found in size distribution was found for 90days. Our result indicates that the developed ethosomal system may be potential and safe to delivery paroxetine hydrochloride through transdermal deliverys. INTRODUCTION: In recent years the attraction of lipid vesicle use in delivery system for skin treatment is increasing (1, 2). Paroxetine hydrochloride (PXH) is a selective serotonin reuptake inhibitor. Commonly available in tablets and capsule dosage form, but oral administration have numbers of side effects as well as it undergoes extensive hepatic metabolism. Variation in plasma concentration and long term therapy leads to severe side effects (3). To overcome these difficulties such as extensive hepatic first pass metabolism transdermal delivery is beneficial (4). The useful of transdermal delivery has been proved for some antidepressants (5,6). It is previously reported that significant increase delivery of drugs across the skin would be done by using an ethosomes as novel permeation enhancing carrier (7-10). Composition of ethosomes system mainly contains phospholipids, ethanol and water (12). Solubility and high encapsulation efficiency values for large range of lipophilic drugs can be obtain due to presence of ethanol. Ethanol may provide vesicles with soft flexible characteristics, which allow them to penetrate more simply into the deeper layers of the skin (13). The present aim focuses on the preparation and characterization of ethosomal formulation for PXH transdermal delivery. The aim of present study was to develop stable ethosomes carrier for transdermal delivery of PXH. The effect of ethanol and soya lecithin on the permeation of PXH through the human skin was evaluated. Material and method: Material: Soya lecithin was purchased from Research Lab Mumbai. Ethanol was purchased from Loba chemical Mumbai. Cholesterol was purchased from Research Lab Fine Chem Industries, Mumbai. PEG-400 was purchased from Dipa Laboratory Chemicals. All materials and solvents used in this study are of analytical grade. Preparation of ethosomes: Soya lecithin and PXH, were dissolved in ethanol. Double distilled water was added slowly with a fine stream in above ethanol dispersion with constant mixing at 700 rpm on magnetic stirrer, in a well-sealed glass container. Mixing was continued for an additional 5 min. The system was kept at 300C throughout the preparation and was then left to cool at room temperature. (7, 8) PHYSICAL CHARACTERISATION OF ETHOSOME: Vesicles size distribution, polydispersity index and zeta potential The vesicle size distribution, polydispersity index and zeta potential of vesicles was determined using photon correlation spectroscopy (Beckmann counter, Delsa Nano, USA). Formulation were diluted by 1/4th distilled water before measurement and measured three times at scattering angle of 900. The polydispersity index (PI) was used as a measurement of the width of the size distribution. PI less than 0.4 indicates a homogenous and monodisperse population. Zeta potential was measured as the particle electrophoretic mobility means of laser microelectrophoresis in a thermostated cell. Entrapment efficiency (EE) The entrapment capacity of PXH by ethosomal vesicles was determined by ultracentrifugation. Formulations were kept overnight at 4 micro-centrifuge (Tarsons) 12000 rpm for 30 min. The supernatant was removed and drug amount was determined in both the sediment and the supernatant. The entrapment capacity was calculated as follows, [(T2C) /T] 100, where T is the total amount of drug that is detected both in the supernatant and sediment, and C is the amount of drug detected only in the supernatant. In vitro permeation study Preparation of cadaver skin Skin samples provided from Government Medical College and Hospital, Aurangabad. Obtain from breast reduction operation and subcutaneous fat was carefully trimmed and then rinse with normal saline, prepared skin was warped in aluminium foil and stored at -200c until use. (15) Procedure Invitro skin permeation studies were performed on a Franz diffusion cell with an effective diffusional area 0.785 cm2 and having receptor compartment volume of 15ml. The skin was brought to room temp and mounted with the donor compartment dry and open to the atmosphere. Initially, the donor compartment was empty and receiver compartment was filled with phosphate buffer ph 7.4. The receiver fluid was stirred with magnetic bead with the speed of 100rpm and the temperature was maintained at 371. The phosphate buffer pH 7.4 was replaced with the fresh one at every 30 min to stabilize the skin. It was found that the receiver solution should a negligible peak area after 3hr and beyond indicating complete stabilisation of skin. 5ml ethosomes formulation was placed into the donor compartment and sealed with paraffin film to provide occlusive condition. The sample where withdraw at regular interval for 10 hrs filtered through 0.45 . membrane filter and analysed for drug amount by UV-Visible s pectrophotometer at 294 nm. Permeation data analysis The cumulative amount of penetrant, Q (g/cm2), which permeated the skin per unit surface area was plotted against time. The linear portion of the plot was taken as being the steady-state flux, (Js). The permeability coefficient (Kp) was calculated as: Kp = Js/Cv Where Cv is the concentration of penetrant in the donor solution. Vesicle stability evaluation: Stability of optimised ethosomes formulation was kept at room temp for 4 weeks. The measurement where conducted on of ethosomes that. Vesicle size, polydispersity index and zeta potential was measured at 1, 2, 3, 7, 14 and 21 days mean value where used for the analysed of the data. 2.5. In vivo Pharmacodynamic study Approval to carry out pharmacodynamics studies was obtained (Institutional Animals Ethical Committee, approved the protocol). Forced Swim test (FST) and Locomotor Activity test (LAT) was used to evaluate antidepressant effect of the optimized F2 formulation. Rats of either sex weighing 250–300 g were kept under standard laboratory conditions (temperature 23-30oc).The rats were kept with free access to standard laboratory diet. Approximately 14 cm2 of abdominal side of rats skin was shaved on the in each group except group treated with marketed tablet formulation. Rats were divided randomly into three groups each containing six animals. Group -1 was considered as a control. Group-2 was treated with oral tablet of PXH containing 1.40 mg/day and administered without anaesthesia by using simple poly-ethylene tube. Group-3 was treated with optimized F2 formulation applied transdermally containing 2 mg/day (equivalent to 0.60 mg/day) drug. 2.5.1. Force swim test Rats were forced to swim in cylindrical glass tank (60 cm height X 30 cm in diameter) containing water after the administration of doses. Water was filled up to 40 cm height so they were swim without touching their hind limb or tail to bottom of the tank. On the 1st day of experiments, rats were forced to swim for 10 min. After 24 h, rats were re-exposed to forced swim for 5 min and animals were judged for immobility, climbing, and swimming. After a 5-min swim test, the rat was removed from the cylinder, dried and then returned to its home cage [29]. Porsolt, R.D., Bertin, A., Jalfre M. (1977). Behavioral despair in mice: a primary screening test for antidepressants. Arch Int Pharmacodyn Ther. 229, 327–336. 2.5.2. Locomotor activity Hyperactivity, functional roles of specific neurobiological and drugs potential psycho activity were discriminate by the locomotor activity study [30]. Locomotor activity was measured in the open-field test. The apparatus consisted of a square arena (200Ãâ€"200 cm), with a 50 cm height. The floor was divided into 30 equal squares. Animals were individually positioned in the centre of the arena and the activity was measured over 5 min. The open field was cleaned with isopropyl alcohol solution before behavioural testing to avoid possible bias due to odours and/or residues left by rats tested earlier. Also after each 3 animals apparatus was cleaned [31]. Result and discussion Vesicle size, polydispersity index and zeta potential: The vesicle mean diameters for all formulation are shown in Table 2. The result of photon correlation spectroscopy shows narrow peak for all formulation, which indicating that size of vesicle population is comparatively uniform in size. In accordance with other researcher, this decrease in the mean diameter of vesicle is due to the presence of ethanol (touitou et al., 2000). Higher concentration of ethanol produced lower vesicle size. Probably the ethanol causes the modification of the net charge of the system and confer it some degree of stearic stabilization that may finally lead to decrease in mean particle size (lasic et al., 1998). In the formulation the concentration of ethanol increases from 30-35% the significant decrease in vesicle size. On the other hand, it was observed that the increase in soya lecithin concentration resulted in increase in mean particle size. Small vesicle size is formed with the F2 formulation having a 1% of soya lecithin and 35% ethanol. Twice fold inc rease in soya lecithin concentration (1%-2%) resulted in two fold increase in ethosomes size (from 500nm- ). The charge of vesicles is important parameter that can influence both stability and skin vesicle interaction. Zeta potential value of all formulations shown in Table 2. The concentration of ethanol increase from 30-35% v/v resulting in increase in zeta potential values. Polydispersity index was determined as measure of homogeneity in formulation. Polydispersity index ≠¤ 0.3 indicate homogeneous population of ethosome vesicle in formulation. Polydispersity of all formulation shown in Table 2. Compare to all formulation F2 formulation showed less polydispersity index is 0.23 indicates homogeneous population of ethosome vesicles. Entrapment efficiency Entrapment efficiency of all formulation shown in Table 2. Entrapment efficiency of formulation containing of 1% soya lecithin and 30% (F1) ethanol was found to be 60%, which significantly increased to 64% when the amount of ethanol increases to 35% (F2) keeping the concentration of soya lecithin constant. Ethosomes formulation prepared with 1.5% soya lecithin and 30% ethanol (F3) exhibited 40% entrapment efficiency, which was increased to 45% (F4) respectively; keep the amount of soya lecithin constant. Formulation prepared with 2% soya lecithin and 30% ethanol (F5) showed 42% entrapment efficiency, which was increased to 61% when the concentration of ethanol increased to 35%(F6) respectively. These data supported by previous finding that solubility and high encapsulation efficiency values for large range of lipophilic drugs can be obtain due to presence of ethanol (13).From these results entrapment efficiency of formulation was observed due to increase in ethanol concentration. Invitro permeation study In vitro skin permeation experiment was performed using human cadaver skin showed that permeation was highest in F2 formulation as shown in Fig 1. Flux value of F2 formulation was significantly different when compared with other formulation (P≠¤0.05) as shown in Table 3. Highest flux value (-) of F2 as compared to other formulation. These may be due to small vesicle size and high entrapment efficiency alone with high concentration of ethanol. These data supported by previous finding that ethanol interact with a lipid molecules of stratum corneum, resulting in reduction in the Tm of stratum corneum, increase in there fluidity. The intercalation of ethanol due to polar head group environment can result in increase in membrane permeability (16). It can also suggest that mixing of phospholipids with the stratum corneum lipid of the intercellular layers enhances the permeability of the skin (17). F2 formulation was selected as a optimized formulation from the vesicle size distributio n, polydispersity index, zeta potential, drug entrapment efficiency, and in vitro permeation study results and considered for further study. In vivo Pharmacodynamic study Pharmacodynamic activity of ethosomes F2 formulation was compared with orally administered dose. Pharmacodynamic activity involved two tests. One was force swim test and other was locomotor activity. Force swim test is most widely used model for assessing the antidepressant activity. Total immobility period would decrease if high concentration of paroxetine hydrochloride reached target site. Force swim test Results of FST confirmed that there was significant reduction in total immobility period in seconds by treating the rats by transdermal ethosomal F2 formulation. There was significant (p Table 3. Results of forced swim test. Conclusion: Ethosomal vesicles with appropriate size and maximum drug entrapment efficiency can be prepared. F2 formulation showed highest transdermal flux across human skin was composed of 1% soya lecithin, 35% ethanol and 2% cholesterol. In vivo pharmacodyanamic study of optimised formulation showed significant values compared to controlled group. Therefore, it can be concluded from the result of the study that ethosome formulation is potentially useful carrier for transdermal delivery of paroxetine hydrochloride REFERANCES O. Braun-Falco, H.C. Kortung, H.I. Maibach (Eds.), Grieswith bach Conference: Liposome Dermatics, Springer-Verlag, Berlin, Heidelberg, 1992. E. Touitou, H.E. Junginger, N.D. Weiner, M. Mezei, Lipo somes as carriers for topical and transdermal delivery, J.Pharm. Sci. 9 (1992) 1189–1203. Hollister L E. Norwalk, Connecticut: Appleton Lange; 1995. A Lange Medical Book: Basic and Clinical Pharmacology. 448–59. Kilts CD. Potential New Drug Delivery Systems for Antidepressants: An overview. J Clin Psychiatry. 2003; 64:31–3. Frampton JE and Plosker GL. Selegiline transdermal system: in the treatment of major depressive disorder: Profile report. CNS Drugs. 2007; 21:521–24. Singh G, Ghosh B, Kaushalkumar D and Somsekhar V. Screening of venlafaxine hydrochloride for transdermal delivery: passive diffusion and iontophoresis. AAPS Pharm Sci Tech. 2008; 9:791–797. Touitou E. Compositions for applying active substances to or through the skin. US Patent 5 540 934, 1996. Touitou E, Composition for applying active substances to or through the skin. US Patent 5 716 638, 1998. Touitou E, Alkabes M, Dayan N, Eliaz M. Ethosomes: novel vesicular carriers for enhanced skin delivery. Pharm Res 1997; 14: S-305. Touitou E, Dayan N, Bergelson L, Godin B, EliazM.Ethosomes*novel vesicular carriers for enhanced delivery: characterizationand skin penetration properties. J Control Rel 2000; 65:403}18. Touitou E, Dayan N, Bergelson L, Godin B, Eliaz M. Ethosomes *novel vesicular carriers for enhanced delivery: characterization and skin penetration properties. J Control Rel 2000;65: 403}18. M.M.A. Elsayed, O.Y. Abdallah, V.F. Naggar, N.M. Khalafallah, Deformable liposomes and ethosomes as carriers for skin delivery of ketotifen, Pharmazie 62 (2007) 133–137. Heeremans JLM, Gerristen HR, Meusen SP, Mijuheer FW, Panday GRS, Prevost R, Kluft C, Crommelin DJA. The preparation of tissue-type plasminogen activator (t-PA) containing liposomes: entrapment effciency and ultracentrifugation damage. J Drug Target 1995; 3:301-310. Fang, J,V., Sung, K.C., Lin, H. H., Fang, C.L.(1999) transdermal iontophoretic Delivery of diclofenac sodium from various polymer formulation: Invitro and Invivo studies. Int. J. Pharm. 19 178; 83-92. Nava Dayan., Elka Touitou. (2000) Carrier for skin delivery of trihexphenidyl HCL:ethosomes vs. Liposomes: biomatererials 21( 2000) 1879-1885. A. Blume, M. Jansen, M. Ghyczy, J. Gareis, Interaction of phospholipid liposomes with lipid model mixtures forstratum corneum lipids, Int. J. Pharm. 99 (1993) 219–220. Formulation of ethosome: Table- 1 Evaluation of ethosome:

Dying at a Young Age :: Death Youth Accidents Essays

Dying at a Young Age Death can occur at any age or period in a person’s life. Death is a natural part of life that everyone will one day have to face. So why does it seem so different when a young adult or adolescent dies in comparison to an older adult? Is it so different? My brother lost two of his best friends in the last three years. One in a car accident and one to a terminal illness. I also lost my best friend in a car accident. In this paper we will look at why people consider it so different when a younger person dies, as well as what is appropriate behavior in dealing with death. MT was a fourteen year old boy that was entering his freshman year of high school. MT was very athletic and active young man. One day MT, used to the usual severe headaches that he sometime got, blacked out. His parents rushed him to the emergency room. The doctors believed it was just a seizure. After a couple weeks in the hospital MT was released from the hospital just before Thanksgiving. On Thanksgiving day MT blacked out again. He was again rushed to the hospital. This time doctors believed it was a tumor, but had to wait for the swelling in the brain to go down to do surgery. MT went into a coma, which he never came out of. The doctors finally figured out MT had a rare disease called Moa-Moa. The disease caused the blood vessels in the brain to burst. MT died five days before his fifteenth birthday. CO, a typical high school senior, thought he was invincible. CO decided to drag race one of his friends. As they went around a forty-five mile per hour curve at eighty miles per hour CO left the road. CO was instantly killed as two passengers walked away with a few cuts and bruises. MW, a twenty year old college student, was on her way home for the summer break. MW looked up to see another car in her lane trying to pass a semi.